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Specific age groups, persons who participate in risky sexual behavior, or those have certain health conditions may require screening.

The CDC recommends that sexually active women under the age of 25 and those over 25 at risk should be screened for chlamydia and gonorrhea yearly.

This can be avoided simply by not engaging in sexual contact when presenting open, bleeding wounds.

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Certain STIs, particularly certain persistent viruses like HPV, may be impossible to detect with current medical procedures.

Some treatment facilities utilize in-home test kits and have the person return the test for follow-up.

Prevention counseling is most effective if provided in a nonjudgmental and empathetic manner appropriate to the person's culture, language, gender, sexual orientation, age, and developmental level.

Prevention counseling for STIs is usually offered to all sexually active adolescents and to all adults who have received a diagnosis, have had an STI in the past year, or have multiple sex partners.

The transfer of and exposure to bodily fluids, such as blood transfusions and other blood products, sharing injection needles, needle-stick injuries (when medical staff are inadvertently jabbed or pricked with needles during medical procedures), sharing tattoo needles, and childbirth are other avenues of transmission.

These different means put certain groups, such as medical workers, and haemophiliacs and drug users, particularly at risk.Both partners can get tested for STIs before initiating sexual contact, or before resuming contact if a partner engaged in contact with someone else.Many infections are not detectable immediately after exposure, so enough time must be allowed between possible exposures and testing for the tests to be accurate.Some microorganisms and viruses are small enough to pass through the pores in natural skin condoms, but are still too large to pass through latex or synthetic condoms.In order to best protect oneself and the partner from STIs, the old condom and its contents are be assumed to be infectious.Therefore, the old condom must be properly disposed of.

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