Only when mixed with a highly alkaline substance (such as lime) can it be absorbed into the bloodstream through the stomach.
The efficiency of absorption of orally administered cocaine is limited by two additional factors.
The elixir of carbon-free growth turns out to be snake oil after all. But the same survey found that 68 percent of people were “very dissatisfied” or “somewhat dissatisfied” with the way it had been implemented, only 15 percent were “somewhat satisfied,” and only 1 percent were “very satisfied.” Europe’s energy policies are worse than stupid.
Then two weeks ago, in the protracted talks to form a new governing coalition, Germany’s largest parties dropped the 2020 goal. At the end of last year, Sir John Beddington, a former chief scientific adviser to the British government, lifted the lid on the scandal at the heart of the EU’s renewable policies.
Many users rub the powder along the gum line, or onto a cigarette filter which is then smoked, which numbs the gums and teeth – hence the colloquial names of "numbies", "gummers", or "cocoa puffs" for this type of administration.
This is mostly done with the small amounts of cocaine remaining on a surface after insufflation (snorting).
Ingesting coca leaves generally is an inefficient means of administering cocaine.
Because cocaine is hydrolyzed and rendered inactive in the acidic stomach, it is not readily absorbed when ingested alone.
Some ENT specialists occasionally use cocaine within the practice when performing procedures such as nasal cauterization.
In this scenario dissolved cocaine is soaked into a ball of cotton wool, which is placed in the nostril for the 10–15 minutes immediately before the procedure, thus performing the dual role of both numbing the area to be cauterized, and vasoconstriction.
First, the drug is partly catabolized by the liver.