Though he had served as Acting President as early as 1934, Jones' son, Bob Jones, Jr.
officially became the school's second president in 1947 just before the college moved to Greenville, South Carolina, and became Bob Jones University.
Bankrupt at the nadir of the Depression, without a home, and with barely enough money to move its library and office furniture, the college became in thirteen years the largest liberal arts college in Tennessee.
With the enactment of GI Bill at the end of World War II, the college was virtually forced to find a new location and build a new campus.
grew increasingly concerned about the secularization of higher education and the influence of religious liberalism in denominational colleges.
Children of church members were attending college, only to reject the faith of their parents.
Negative publicity caused by the dispute precipitated a decline in BJU enrollment of about 10% in the years 1956–59, and seven members of the university board (of about a hundred) also resigned in support of Graham, including Graham himself and two of his staff members.
Enrollment quickly rebounded, and by 1970, there were 3300 students, approximately 60% more than in 1958.
In 2004, the university began the process of joining the Transnational Association of Christian Colleges and Schools. 574), the university chose to maintain its interracial dating policy and pay a million dollars in back taxes.
Candidate status—effectively, accreditation—was obtained in April 2005, and full membership in the Association was conferred in November 2006. After BJU lost the decision in Bob Jones University v. The year following the Court decision, contributions to the university declined by 13 percent.
In 2008, the university estimated the number of its graduates at 35,000; in 2017, 40,184.
During the Fundamentalist-Modernist controversy of the 1920s, Christian evangelist Bob Jones, Sr.
Jones later recalled that in 1924, his friend William Jennings Bryan had leaned over to him at a Bible conference service in Winona Lake, Indiana, and said, "If schools and colleges do not quit teaching evolution as a fact, we are going to become a nation of atheists." While he himself was not a college graduate, Jones grew determined to found a college, and on September 12, 1927, he opened Bob Jones College in Panama City, with 88 students.